In vitro & in vivo evidences

Tosi G et al, Brain-targeted polymeric nanoparticles: in vivo evidences of different routes of administration in rodents. Nanomedicine (Lond). 2013, 8, 1373-1383. [Link]

Vilella A, et al. Insight on the fate of CNS-targeted nanoparticles. Part I: Rab5-dependent cell-specific uptake and distribution. J Control Release 2014, 174:195-201. [Link ]

Tosi G, et al., Insight on the fate of CNS-targeted nanoparticles. Part II: Intercellular neuronal cell-to-cell transport. J Control Release 2014, 177:96-107. [Link]

Monsalve Y, et al.,  PEG-g-chitosan nanoparticles functionalized with the monoclonal antibody OX26 for brain drug targeting. Nanomedicine (Lond) 2015, 10:1735-1750. [Link]

Vilella A, et al., Endocytosis of nanomedicines: The case of glycopeptide engineered PLGA nanoparticles. Pharmaceutics, 2015, 7:74-89. [Link]

Chhabra R, et al.  Application of polymeric nanoparticles for CNS targeted Zinc delivery in vivo. CNS Neurol Disord Drug Targets 2015, 14:1041-1053. [Link]

Tosi G, et al. Exploiting bacterial pathways for BBB crossing with PLGA nanoparticles modified with a mutated form of Diphtheria Toxin (CRM197): In vivo experiments. Mol Pharm. 2015, 12:3672-3684. [Link]

Giordani M et al., Whole organic electronic synapses for dopamine detection, Proceedings of SPIE - The International Society for Optical Engineering, 2016, 99440P-99440P-7. (2016) [Link]

Mapelli J, et al., Heterosynaptic GABAergic plasticity bidirectionally driven by the activity of pre- and postsynaptic NMDA receptors. Proc Natl Acad Sci U S A. 2016 113, 9898-903. [Link]

Gandolfi D, et al., Long-Term Spatiotemporal Reconfiguration of Neuronal Activity Revealed by Voltage-Sensitive Dye Imaging in the Cerebellar Granular Layer. Neural Plast. 2015, 284986. [Link]

Volpi N et al., High-performance liquid chromatography-mass spectrometry for mapping and sequencing glycosaminoglycan-derived oligosaccharides, Nature Prot, 2015, 5, 993-1004. [Link]

Salio C, et al., GABAB receptors-mediated tonic inhibition of glutamate release from Abeta fibers in rat laminae III/IV of the spinal cord dorsal horn. Molecular pain, 2017, 13, 1-16. [Link]

Betelli C et al. Transient, activity dependent inhibition of transmitter release from low threshold afferents mediated by GABAA receptors in spinal cord lamina III/IV. Molecular pain, 2015, 11, 64. [Link]

Bardoni R, et al. Delta opioid receptors presynaptically regulate cutaneous mechanosensory neuron input to the spinal cord dorsal horn. Neuron, 2014, 1:1312-27. [Link]

Morelli FF, et al. S. Aberrant compartment formation by HSPB2 mislocalizes lamin A and compromises nuclear integrity and function. Cell Reports, 2017 [Link]

Rusmini P, et al.,. The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases. Front Mol Neurosci. 2017, 10:176.  [Link]

Alberti S, et al., Granulostasis: protein quality control of RNP granules, Front Mol Neurosci. 2017, 10, 84. [Link]

Mateju D, et al., An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function. EMBO J. 2017, e201695957 [Link]

Cristofani R, et al. Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases. Autophagy. 2017. [Link]

Piccolella M, et al, The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells. Oncotarget. 2017, 8, 10400-10415. [Link]

Ganassi M, et al., A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism. Mol Cell. 2016, 63, 796-810. [Link]

Crippa V, et al.,. The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity. Hum Mol Genet. 2016, pii: ddw232 [Link]

Crippa V, et al., Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases. Sci Rep. 2016, 6, 22827. [Link]

Seguin SJ, et al., Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly. Cell Death Differ. 2014, doi: 10.1038/cdd.2014.103. [Link]

Cancer

Orsi G, et al., GD2 expression in breast cancer. Oncotarget. 2017, 8, 31592-31600. [Link]

Baglio SR, et al. Blocking Tumor-Educated MSC Paracrine Activity Halts Osteosarcoma Progression. Clin Cancer Res. 2017, 23, 3721-3733. [Link]

Critelli R, et al. Microenvironment inflammatory infiltrate drives growth speed and outcome of hepatocellular carcinoma: a prospective clinical study. Cell Death Dis. 2017, 8, e3017. [Link]

Civallero M, et al., Calcium-Carbonate Nanocapsules Improve the Efficacy of BEZ235 in Lymphoma a Cell Line: A Promising New Technology of Drug Delivery, Blood 2015 126:4851 [Link]

Serafin V, et al, Phosphoproteomic analysis reveals hyperactivation of mTOR/STAT3 and LCK/Calcineurin axes in pediatric early T-cell precursor ALL. Leukemia. 2017, 31, 1007-1011. [Link]

Mediani L, et al, Reversal of the glycolytic phenotype of primary effusion lymphoma cells by combined targeting of cellular metabolism and PI3K/Akt/ mTOR signaling. Oncotarget. 2016, 7, 5521-37. [Link]

Bertacchini J, et al.,. Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis. Leukemia. 2014, 28, 2197-205. [Link]

Inflammation & Infection

Paulone S, et Candida albicans survival, growth and biofilm formation are differently affected by mouthwashes: an in vitro study. New Microbiol. 2017, 40(1). [Link]

Paulone S, et al, The synthetic killer peptide KP impairs Candida albicans biofilm in vitro. S, PLoS One. 2017, 12, e0181278. [Link]

Pericolini E, et al. Therapeutic activity of a Saccharomyces cerevisiae-based probiotic and inactivated whole yeast on vaginal candidiasis. Virulence. 2017, 8, 74-90. [Link]

Vecchiarelli A, et al. Experimental models of vaginal candidiasis and inflammation. Future Microbiol. 2015, 10, 1265-8. [Link]

Gabrielli E, et al. Comparison between bioluminescence imaging technique and CFU count for the study of oropharyngeal candidiasis in mice. Cytometry A. 2015, 87, 428-36. [Link]

Pini P, et al. Clinical performance of a commercial real-time PCR assay for Aspergillus DNA detection in serum samples from high-risk patients: comparison with a galactomannan enzyme immunoassay. Eur J Clin Microbiol Infect Dis, 2015, 34, 131-6. [Link]

Orsi CF et al., Inhibitory effects of different Lactobacilli on Candida albicans hyphal formation and biuofilm development. J Biological Regulators &Homeostatic Agents , 2014, 28, 743-752. [Link]

Ardizzoni A, et al.- An antibody reactivity-based assay for diagnosis of invasive candidiasis using protein array. Intln J immunopharmacol & Immunopathol, 2014, 27, 403-12. [Link]

Messi P, et al, Legionella pneumophila in health-care setting: sensitivity to biocidal treatments in mono- and multi-species biofilms.  J Hosp Infect, 2017, [Link].  

Condò C, et al, Antimicrobial activity of silver doped fabrics for the production of hospital uniforms. New Microbiologica, 2015, 38, 551-558. [Link]

Anacarso I, et al., Anti-listerial activity of chitosan and Enterocin 416K1 in artificially contaminated RTE products. Food control, 2011, 22, 2076-2080. [Link]

Iseppi R, et al, Anti-listerial activity of coatings entrapping living bacteria. Soft Matter, 2011, 7, 8542-8548 [Link]

Iseppi R, et al, Anti-listerial activity of a polymeric film coated with hybrid coatings doped with Enterocin 416K1 for use as bioactive food packaging Int. J. Food Microbiol., 2008, 123, 281. [Link]

Borella P, et al, Hospital-acquired Legionella infections: an update on the procedures for controlling environmental contamination. Ann Ig. 2016, 28, 98-108. [Link]

Marchesi I, et al, Control of Legionella Contamination and Risk of Corrosion in Hospital Water Networks following Various Disinfection Procedures. Appl Environ Microbiol. 2016, 82, 2959-65. [Link]